It carries two main instruments: the Large Area Telescope (LAT) and the Burst Monitor (GBM). The first instrument will be used to reconstruct images at very high energies (photons with up to 300 GeV which are radiated by the most energetic events in the Universe). The second instrument is used to detect short-lived sources such as the Gamma-Ray Bursts of which around 200 will be discovered annully (around the same rate as Swift, which is dedicated to discovering GRBs).
Links
GLAST
Swift